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. 2017 May 19;8(28):46348–46362. doi: 10.18632/oncotarget.18013

Table 5. The impact of PARP1-low and high mRNA expression levels in the p53 pathway.

Genes PARP1 levels1 p-Value ± SE2 95% CI3
Low High Lower Upper
CDKN1A 0.075 −0.227 0.009 0.113 0.077 0.526
CDKN2A −1.117 −1.029 0.560 0.151 −0.387 0.210
MDM2 2.363 5.240 0.310 2.819 −8.472 2.717
MDM4 0.614 2.366 0.310 1.718 −5.151 1.647
TP53 −0.278 0.225 0.003 0.164 −0.828 −0.178
TP53BP1 −0.520 −0.052 0.004 0.161 −0.787 −0.150

(Significant p-values are marked in bold.)

1Mean mRNA z-scores; 2standard error; 3confidence of interval.