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. 2017 Aug 3;12(8):e0182183. doi: 10.1371/journal.pone.0182183

Fig 1. CD133/Nestin/CD34 Expression in Glioblastoma, CD133 (Purple), Nestin (Red), CD34 (Green). Nuclei are Counter stained with DAPI (Blue).

Fig 1

(A) microvascular sprouting (MS), many Nestin and CD133 positive cells are scattered; (B) vascular cluster (VC), the Nestin and CD133 positive cells have a regional maldistribution; (C) vascular garland (VG), a mass of Nestin positive cells are accumulated as a cluster. Nestin was expressed not only on GSCs but also in the brain capillaries on endothelial cells, and CD133 positive cells accumulated around the blood vessels; (D) glomeruloid vascular proliferation (GVP), with a large number of Nestin and CD133 positive cells in the periphery of vessels and fewer in the avascular area. Nuclei are always counterstained with DAPI (Blue).