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. 2017 Aug 3;12(8):e0181806. doi: 10.1371/journal.pone.0181806

Fig 8. Migration of NPDFs facilitated by IL-25 facilitated the migration of NPDFs.

Fig 8

Migration cells were examined by a cell migration assay. Photos of our microscopic observations of cell migration assays showing nasal fibroblast migration by IL-25 and pretreatment with specific inhibitors after 24h (A) and 48h (BC). The number of fibroblasts was counted in a ‘cell-free gap’ (500μm in width) after 24h and 48h (C). Values are expressed as means ± standard errors of independent experiments. *P<0.05 vs control; †p <0.05 vs IL-25 alone; ∇p <0.05 vs 24hr. Scale bar = 500 μm; Triple tests were performed on all of the experiments. U = specific inhibitor of ERK, SB = specific inhibitor of p38, SP = specific inhibitor of JNK, Bay = specific inhibitor of U = specific inhibitor of NF-κB.