Skip to main content
. 2017 Aug 3;12(8):e0182092. doi: 10.1371/journal.pone.0182092

Fig 1. Behavioral and immunohistochemical analysis of transgenic mice and their wild-type littermates.

Fig 1

(A) RT-PCR was used to verify the mRNA expression of α-synuclein-A30P*A53T transgenic mice (TG) and wild-type littermates (WT). (B) The rotarod test was used to measure TG mice and WT controls at the age of 6 months (n = 15). (C) Grip strength tests were performed in TG mice and WT controls (n = 15). (D and E) Open field tests were performed in TG mice and WT controls (n = 15). (F) Immunostaining of tyrosine hydroxylase (TH)-positive neurons of SNpc in TG mice and WT controls. (G) The number of TH-immunoreactive positive neurons in the SNpc was counted stereologically (n = 3).