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. 2017 Aug 3;12(8):e0182294. doi: 10.1371/journal.pone.0182294

Fig 3. Single-gene biomarker for HIV-1 infection.

Fig 3

(A), (B) Progressors and non-progressors of HIV-1 infection can be distinguished using the expression of ISG15. (C,), (D) Treatment effect can also be monitored using the expression of ISG15. In dataset GSE44228, Samples were after treatment with antiretroviral therapy (ART). In the upper panel, fold induction was calculated against the median level of healthy controls. In the lower panel, fold reduction was calculated against the pre-treatment level of the same patient.