Table 1. Chronic effects of treadmill exercise on the mRNA expression in the soleus muscle of C57BL/6 PAD mice.

Gene	Sedentary sham-operated	Sedentary PAD	Exercised PAD
Pgc1a	1.00 ± 0.38	2.87 ± 0.64††	2.26 ± 1.03
Il6	1.00 ± 0.54	1.41 ± 0.35	1.26 ± 0.38
Nr4a1	1.00 ± 0.56	0.66 ± 0.56	0.80 ± 0.11
Nr4a2	1.00 ± 0.37	1.71 ± 0.95	1.61 ± 0.39
Nr4a3	1.00 ± 1.07	1.16 ± 0.21	0.85 ± 0.33
Myf5	1.00 ± 0.15	1.79 ± 0.20††	1.46 ± 0.11‡
Myogenin	1.00 ± 0.35	3.18 ± 0.83††	1.63 ± 0.50‡
Myomaker	1.00 ± 1.08	11.7 ± 5.18††	5.91 ± 3.86
Myh3	1.00 ± 0.42	12.7 ± 3.26††	10.9 ± 4.24
Gpr56	1.00 ± 0.22	1.77 ± 0.50†	1.22 ± 0.40
Col3a1	1.00 ± 0.02	11.0 ± 1.78††	6.70 ± 0.98‡‡

Results are expressed as the mean ± SD; sedentary sham-operated mice (n = 3), sedentary PAD mice (n = 5), and exercised PAD mice (n = 4)

^†p < 0.05,

^††p < 0.01 vs. sedentary sham-operated mice (Student's or Welch's t-test).

^‡p < 0.05,

^‡‡p < 0.01 vs. sedentary PAD mice (Student's or Welch's t-test).