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. 2017 Aug 3;12(8):e0182444. doi: 10.1371/journal.pone.0182444

Table 3. Results of univariate and multivariate analyses.

Covariate OS DFS
Univariate Multivariate Univariate Multivariate
HR (CI 95%) P-value HR (CI 95%) P-value HR (CI 95%) P-value HR (CI 95%) P-value
Age 0.98(0.94–1.02) 0.35 1.00(0.97–1.03) 0.84
Size 1.19(1.15–1.45) 0.07 1.00(0.78–1.28) 0.98 1.15(0.98–1.34) 0.09 0.94(0.77–1.15) 0.54
Grade (3 over 1 or 2) 3.66(1.44–9.29) 0.01 2.93(0.91–9.46) 0.07 2.57(1.18–5.58) 0.02 2.61(0.97–7.00) 0.06
Stage 2 0.73(0.14–3.74) 0.70 0.40(0.07–2.37) 0.32 0.39(0.11–1.38) 0.14 0.23(0.06–0.90) 0.03
3 3.26(0.73–14.63) 0.12 2.22(0.36–13.63) 0.39 2.81(0.97–8.20) 0.06 2.11(0.56–8.00) 0.27
ER or PR(Positive over Negative) 0.33(0.13–0.82) 0.02 0.42(0.15–1.18) 0.10 0.42(0.21–0.85) 0.02 0.48(0.20–1.14) 0.10
HER2/neu(Positive over Negative) 1.54(0.58–4.06) 0.38 1.57(0.74–3.34) 0.24
P53 4.22(1.60–11.11) 0.00 5.04(1.71–14.94) 0.003 2.74(1.34–5.60) 0.01 3.81(1.68–8.64) 0.001
Menopause (menopause over pre-menopause) 0.96(0.37–2.54) 0.94 1.15(0.55–2.40) 0.70