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. 2017 Aug 3;12(8):e0182698. doi: 10.1371/journal.pone.0182698

Fig 3. Sustained effects of ZL006 in Flinders Sensitive Line rats and B6NTac mice.

Fig 3

A: Immobility of Flinders Sensitive Line rats in the Forced Swim Test at baseline (15 min pretest) and at 5-min test sessions 24 h and 72 h after injection of vehicle or ZL006 (15 mg/kg). Rats were more immobile 72 h after injections; ¤: p ≤ .05 compared with the pretest; n = 7/group. B: Immobility of B6NTac mice in 6-min Tail Suspension Test sessions at baseline (pretest) and 24 h and 72 h after injection of vehicle or ZL006 (10 mg/kg); n = 11–13/group. Values are expressed as means ± SEM and were analyzed using a three-way mixed ANOVA (A) and one-way ANOVA (B) followed by pairwise comparisons.