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. 2017 Apr 20;25(8):1805–1814. doi: 10.1016/j.ymthe.2017.04.002

Figure 2.

Figure 2

Enforced Expression of RPS19 Derived from the EFS Promoter Is Sufficient to Rescue the DBA Phenotype In Vitro

c-Kit-enriched hematopoietic progenitors (0.5 × 106) from the BM of uninduced mice were transduced and seeded in liquid culture or methyl cellulose in the presence of doxycycline. (A) Experimental design. (B) Total cell counts on day 8 after growth in liquid culture. (C) Total erythroid colony counts in methyl cellulose cultures (M3436) in the presence of doxycycline on day 14. Data shown in (B) and (C) represent the average of three independent experiments with three technical replicates. *p < 0.05; ***p < 0.001. Wt, wild-type.