Table 2.
IS Analysis in Sequential Liver Biopsies
| ID | Postnatal Challenge (Months) | Hepatic Integration Sequences and Concatemers |
|||||
|---|---|---|---|---|---|---|---|
| Biopsy Time Points (Months) | Total IS | Mappable IS | IS/μg | IS (%) | Concatemers (%) | ||
| 8006 | – | 18 | 427,064 | 3 | 2 | 100.0 | 0.0 |
| 8007 | 46 | 47 | 27 | 6 | 4 | 61.4 | 38.6 |
| 5002 | – | 24 | 608 | 111 | 74 | 87.4 | 12.6 |
| 5006 | 32 | 35 | 2 | 2 | 1.3 | 0.01 | 99.99 |
| 5007 | – | 49 | 550,809 | 6 | 4 | 100.0 | 0.0 |
Detailed summary of the IS retrieved by LAM-PCR. Total IS, number of retrieved sequences corresponding to vector-genome junctions; mappable IS, number of exactly mappable IS; % IS and concatemers, relative sequence count with respect to vector positive reads. ID, identity number.