Table 2.

Univariate and Multivariate Analyses of Factors Associated with Progression-Free Survival in 309 PCa Patients in TCGA

Variable	Univariate			Multivariate
	HRa	95% CI	p Value	HRa	95% CI	p Value
Age, years (>60/≤60)	0.912	0.496–1.677	0.768			NA
Gleason score [7(4+3)–10 / 6–7(3+4)]	0.853	0.624–1.167	0.321			NA
Tumor stage (T3-4/T2)	0.453	0.241–0.853	0.014b	0.399	0.211–0.754	0.005b
Nodal metastasis (N1/N0)	0.809	0.528–1.241	0.331			NA
HOXD-AS1 (high/low)	2.453	1.131–5.318	0.023b	2.827	1.297–6.161	0.009b

Univariate and multivariate analyses were performed. Cox proportional hazards regression model was used. Variables associated with survival by univariate analyses were adopted as covariates in multivariate analyses.

^aHR > 1, risk for death increased; HR < 1, risk for death reduced.

^bSignificant p values.