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. 2017 Aug 3;12(8):e0182427. doi: 10.1371/journal.pone.0182427

Fig 2. mRNA expression of human leucocyte antigen DR alpha (HLA-DRA) is lowest in sepsis patients.

Fig 2

HLA-DRA levels are significant reduced in all patients (n = 40) when compared to controls (n = 10). HLA-DRA levels in patients with sepsis (group B, n = 10) are lowest and significantly reduced when compared to postoperative patients (group A, n = 10). Total mRNA was prepared from whole blood and HLA-DRA expression were assessed by quantitative polymerase chain reaction (qPCR). mRNA levels are normalized to peptidylpropylisomerase B (PPIB) using the delta-delta Ct method. Box and whisker plots with median and interquartile range are presented and statistical analysis was performed using non-parametric Mann-Whitney-U test. P<0.05:*; P<0.001:***.