Table 2.

Single nucleotide polymorphisms associated with risk of primary graft dysfunction.

Gene	Protein or pathway	SNP	Odds ratio	95% confidence interval	Reference
RECIPIENT GENETICS
Ptx3	Pentraxin-3	rs2120243	1.5	1.1–1.9	[27]
		rs2305619	1.4	1.1–1.9	[27]
Ptges2	Prostaglandin E2 synthase	rs13283456	2.0	1.4–2.9	[29]
Ptger4	Prostaglandin E receptor	rs4434423	0.5	0.4–0.8	[29]
		rs4133101	0.6	0.5–0.8	[29]
		rs11957406	1.7	1.3–2.3	[29]
Tbc1d1	Cell growth and obesity	rs2996044	0.5	0.4–0.7	[29]
		rs2925956	0.6	0.4–0.8	[29]
		rs13132184	0.5	0.3–0.7	[29]
Pmch	Neuronal signaling	rs7973796	0.6	0.5–0.8	[29]
F13a1	Coagulation factor XIII	rs3024388	1.8	1.3–2.5	[29]
Gaa	Glycogen degradation	rs12452616	1.8	1.3–2.5	[29]
Cav3	Caveolin 3	rs237865	1.7	1.3–2.2	[29]
Col4a1	Type IV collagen	rs17588591	1.7	1.3–2.3	[29]
Casp8	Caspase 8	rs16836965	3.2	1.7–6.0	[29]
Irx4	Cardiac development	rs260400	2.1	1.4–3.1	[29]
Itgb5	Integrin beta 5	rs3772843	1.9	1.3–2.6	[29]
Prkg1	Platelet aggregation	rs1881597	0.6	0.4–0.8	[29]
Ftcd	Folate metabolism	rs17004504	2.9	1.6–5.2	[29]
Tollip	Toll interacting protein	rs3168046	1.4	1.1–1.8	[30]
Il17R	IL-17 receptor	rs882643	2.2	1.1–4.5	[31]
		rs2241049	2.3	1.3–3.9	[31]
Nfe2l2 (Nrf2)	Nuclear factor (erythroid-derived 2)-like 2	rs6726395	0.8	0.6–1.0	[32]
		rs1806649	0.8	0.6–1.0	[32]
Gpx1	Glutathione peroxidase	rs9818758	0.7	0.5–1.0	[32]
		rs1800668	0.7	0.6–0.9	[32]
		rs3811699	0.7	0.6–0.9	[32]
DONOR GENETICS
Nox3	NAPDH oxidase 3	rs3749930	0.4	0.2–0.8	[32]
		rs231956	1.5	1.1–2.1	[32]
		rs13207865	1.6	1.1–2.3	[32]
		rs231948	0.6	0.3–1.0	[32]
		rs1546894	0.3	0.1–0.9	[32]