Table 1.
Anandamide hydrolysis | Oleamide hydrolysis | ||
---|---|---|---|
Brain | +/+ | 0.33 ± 0.04 | 0.24 ± 0.03 |
+/− | 0.20 ± 0.03 | 0.15 ± 0.01 | |
−/− | 0.003 ± 0.002 | 0.004 ± 0.002 | |
Liver | +/+ | 0.53 ± 0.06 | 0.54 ± 0.01 |
+/− | 0.29 ± 0.03 | 0.29 ± 0.07 | |
−/− | 0.01 ± 0.01 | 0.03 ± 0.01 |
Fatty acid amide hydrolytic activities were measured as described in Materials and Methods.