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. 2017 Jul 24;11(7):e0005799. doi: 10.1371/journal.pntd.0005799

Table 1. Commonly overexpressed transcripts in Ae. aegypti from Funchal and Paul do Mar belonging to detoxification gene families.

Class of detoxification gene Gene accession number Gene name Funchal vs Rockefeller (FC) P-value Funchal vs New Orleans (FC) P-value Paul do Mar vs Rockefeller (FC) P-value
P450s AAEL008846 Cyp9J32 41 0.006 53 0.004 10 0.060
AAEL014617 Cyp9J28 31 0.028 30 0.019 10 0.008
AAEL014893 Cyp6BB2 15 0.005 19 7*10−4 3.6 0.006
AAEL014607 Cyp9J27 14 0.021 18 0.018 3.5 0.023
AAEL014616 Cyp9J27 14 0.020 16 0.016 4.6 0.006
AAEL001288 Cyp9M5 6.6 6*10−4 8.5 0.009 2.3 0.001
AAEL001312 Cyp9M6 5.4 0.015 4.7 0.006 4 0.031
AAEL009124 Cyp6N12 5.1 3*10−4 6.3 0.003 2.2 0.002
AAEL017297 Cyp6M9 4.2 0.007 3.7 0.001 3 0.047
Esterases AAEL005112 CCEae3a 2.7 0.009 3.4 0.012 2.1 0.001
GSTs AAEL001054 GSTd4 24 4*10−4 22 2*10−4 9.8 0.004
AAEL011741 GSTs1 4.9 2*10−4 2.5 7*10−5 2.2 0.032

FC represents the relative fold change in expression in the Funchal or Paul do Mar population compared to the respective susceptible colony. Bold type indicates a known insecticide metabolizer [13,14,40].