Fig 2. Vag8 inhibits the CP and LP but not the AP.

Using complement ELISAs, we show that Vag8 dose dependently inhibits C5b-9 deposition of the (A) CP and (B) LP but not of the (C) AP. The dashed line indicates complement activation in buffer only. Data shown in A-C represent the mean ± SEM of three separate experiments. Significant differences compared to Buffer are indicated with a * * p≤0.05, ** p≤0.01, *** p≤0.001.