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. 2017 Apr 22;4(3):365–370. doi: 10.1002/ehf2.12139

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© 2017 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Histology and immunohistochemistry findings from right ventricular endomyocardial biopsy, of active autoimmune myocarditis. Haematoxylin and eosin staining (×200) shows inflammatory infiltrates (arrows) associated with necrosis of adjacent myocytes (cytoplasmic vacuolation and nuclear atypia of myocytes—asterisks) (A). The immunohistochemistry (original magnification of 400×) shows the presence of CD4 positive cells (B), CD8 positive cells (C), and scattered macrophages [CD68 positive cells, (D)]. There is immunostaining for C4d.