Table 1.
Clinical and hematological features of the patients included in the study and results of the conventional diagnostic workup
| Variable | Value |
|---|---|
| Learning cohort | |
| No. of patients | 683 |
| Age, median (range), y | 66 (18-92) |
| Sex, M/F | 388/295 |
| Hemoglobin, median (range), g/dL | 11.2 (5-16.6) |
| Mean cell volume, median (range), fL | 94 (60-125) |
| White blood cell count, median (range), ×109/L | 4.19 (0.19-15.82) |
| Absolute neutrophil count, median (range), ×109/L | 1.9 (0.03-12.62) |
| Platelet count, median (range), ×109/L | 127 (1-496) |
| Diagnosis according to the outcome of conventional diagnostic workup | |
| Myeloid neoplasm | 409 |
| MDS | 233 |
| Myelodysplastic/myeloproliferative neoplasm | 86 |
| Myeloproliferative neoplasm | 35 |
| Acute myeloid leukemia | 55 |
| Other cytopenias | 120 |
| Aplastic anemia | 30 |
| Lymphoid neoplasm | 28 |
| Other (iatrogenic, immune, and secondary cytopenia) | 62 |
| ICUS | 154 |
| Validation cohort | |
| No. of patients | 190 |
| Age, median (range), y | 62 (19-88) |
| Sex, M/F | 105/85 |
| Time from first evaluation to harvest, median (range), d | 124 (1-436) |
| Diagnosis according to the outcome of conventional diagnostic workup | |
| Myeloid neoplasm | 138 |
| ICUS | 14 |
| Other cytopenias | 38 |
F, female; M, male.