Table 1.
Peptide | Peptide sequence | Survival activitya | FN/PDGF-BB binding inhibitionb |
Control
c Dose (%) Max dilation |
Stress
c Dose (%) Max dilation |
||
---|---|---|---|---|---|---|---|
EVA-1 | PSHISKYILRWRPK | Yes | 95.5% | 10−9M | 22% | 10−13M | 32% |
P18 | YILRWRPK | No | 26% | 10−8M | 26% | – | – |
P7 | ILRWRPK | No | 0.1% | 10−8M | 28% | 10−12M | 29% |
P39 | LRWRPK | No | 0.0% | 10−11M | 8% | – | – |
P37 | RWRPK | No | 0.0% | 10−11M | 19% | 10−15M | 45% |