Table 2.
Variable | Mean (SD) or % | Range |
---|---|---|
Demographics | ||
Age | 58.2 (6.5) | 50 – 79 |
Sex (% Male) | 88% | – |
Education | 14.3 (2.6) | 8 – 20 |
Race (% White) | 82% | – |
HIV Characteristics | ||
Current CD4* | 597 (365.0 – 776.0) | 6 – 1,606 |
Nadir CD4* | 135.5 (39.5 – 300.0) | 0 – 850 |
AIDS Status (% Yes) | 66% | – |
ART status (% On) | 98% | – |
Plasma Viral Load (% Undetectable) | 92% | – |
Est. Duration HIV Infection (yrs) | 18.0 (8.0) | 1 – 30 |
Comorbidities | ||
Hypertension (% with) | 50% | |
Diabetes (% with) | 26% | |
HCV (% with) | 22% | |
Mental Health | ||
Beck Depression Inventory Score* | 8 (3 – 16.8) | 0 – 44 |
Lifetime MDD Diagnosis (% Yes) | 60% | – |
Current MDD Diagnosis (% Yes) | 14% | – |
Lifetime Substance Diagnosis (% Yes) | 70% | – |
Current Substance Diagnosis (% Yes) | 6% | – |
Gold Standard Neurocognitive Impairment (% Yes) | 57% | – |
MoCA Impaired (<=26) | 67% | |
MoCA Total Score | 25.2 (3.0) | 15 – 30 |
Functional Measures | ||
IADL Declines* | 1 (0 – 2) | 0 – 9 |
Cognitive Symptoms* | 2 (0 – 9) | 0 – 31 |
Karnofsky Score | 87.2 (10.6) | 50 – 100 |
IADL Dependent ** | 20% |
Notes
ART=antiretroviral therapy; IADL = instrumental activities of daily living; MDD=Major Depressive Disorder.
Median (IQR) reported for these variables.
Component for the everyday functioning impairment criteria for HIV-associated neurocognitive disorders.