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. 2017 Jul;9(7):2142–2158. doi: 10.21037/jtd.2017.06.20

Table 2. Driver alterations in lung ADC.

Genetic abnormality Frequency (%)
TCGA data cBioPortal data
Mutations
   KRAS 32.2 33
   EGFR 11.0 14
   BRAF 7.0 10
   NF1 8.3 11
   MET ex14 4.3 8
   RIT1 2.2 2
   ERBB2 1.7 1
   MAP2K1 0.9 <1
   NRAS, HRAS 0.8 <1
Amplifications
   MET 2.2 4
   ERBB2 0.9 3
Translocations
   ROS1 1.7 2
   ALK 1.3 3–8
   RET 0.9 1