Table 1. Baseline demographic and medical history characteristics of 123 asthma patients.
| Variables | Total (n=123) | Non-OSA (n=45) | OSA (n=78) |
|---|---|---|---|
| Clinical characteristics | |||
| Men/Total | 71 (57.72) | 14 (31.11) | 57 (73.08) |
| Age (years) | 47.56±12.12 | 40.93±10.03 | 51.38±11.62 |
| Age ≥50 | 54 (43.9) | 8 (17.78) | 46 (58.97) |
| BMI (kg/m2) | 26.42±2.99 | 24.6±2.06 | 27.47±2.94 |
| BMI ≥30 | 15 (12.20) | 0 (0) | 15 (19.23) |
| BMI ≥35 | 2 (1.63) | 0 (0) | 2 (2.56) |
| Neck circumference (cm) | 36.27±2.97 | 33.82±2.22 | 37.67±2.38 |
| Neck circumference ≥40 | 19 (15.45) | 0 (0) | 19 (24.36) |
| Current and Ex-smoker | 37 (30.08) | 8 (13.33) | 29 (37.18) |
| Current and Ex-drinker | 73 (59.32) | 21 (46.34) | 52 (66.23) |
| HBP | 39 (31.36) | 6 (12.20) | 33 (41.56) |
| CHD | 26 (22.03) | 5 (12.20) | 21 (27.27) |
| Arrhythmia | 14 (11.02) | 4 (7.32) | 10 (12.99) |
| GERD | 28 (23.73) | 13 (31.71) | 15 (19.48) |
| Rhinitis | 80 (65.04) | 12 (26.67) | 68 (87.18) |
| Diabetes | 12 (10.17) | 2 (4.88) | 10 (12.99) |
| Dyslipidemia | 48 (40.68) | 8 (19.51) | 40 (51.95) |
| Asthma functional characteristics | |||
| Asthma onset age | 16.43±7.80 | 15.84±8.55 | 16.71±7.41 |
| FeNO (ppb) | 25.54±22.44 | 23.53±22.47 | 26.87±22.59 |
| Lung function data | |||
| FEV1/predicted% | 89.45±12.43 | 92.58±9.75 | 87.63±13.47 |
| FVC/predicted% | 90.51±11.72 | 92.51±9.24 | 89.36±12.85 |
| FEV1/FVC% | 77.23±9.42 | 79.91±9.26 | 75.68±9.22 |
| PEF/predicted% | 86.51±13.09 | 89.30±10.62 | 84.90±14.13 |
| Positive bronchial dilation test | 85 (69.11) | 30 (66.67) | 55 (71.51) |
| Regular medical control of asthma | 81 (66.1) | 31 (68.29) | 50 (64.94) |
| Using ICS | 62 (50.0) | 20 (41.46) | 42 (54.55) |
| Inhaled glucocorticoids, equivalent doses of budesonide (mcg/day) | 361.29±122.69 | 320.00±96.48 | 387.37±132.21 |
| Asthma grade | |||
| Mild | 61 (49.59) | 26 (57.78) | 35 (44.87) |
| Moderate | 54 (43.9) | 17 (37.78) | 37 (47.44) |
| Severe | 8 (6.5) | 2 (4.44) | 6 (7.69) |
| Questionnaire scales | |||
| Asthma control test | 20.71±1.74 | 20.87±1.97 | 20.6±1.58 |
| Berlin questionnaire | 1.16±0.94 | 0.53±0.59 | 1.52±0.91 |
| STOP-Bang questionnaire | 2.80±1.93 | 1.22±1.18 | 3.65±1.73 |
| Polysomnography data | |||
| AHI (/h) | 15.07±12.87 | 2.88±1.50 | 22.28±11.11 |
| ODI (/h) | 15.74±13.24 | 3.54±1.76 | 22.98±11.73 |
| REM (%TST) | 13.00±5.90 | 12.73±6.11 | 13.12±5.83 |
| Average SaO2 | 92.85±3.94 | 95.82±1.71 | 91.13±3.84 |
| Min SaO2 | 82.16±9.45 | 90.44±3.86 | 77.38±8.36 |
Data represent as mean ± SD or number (%). BMI, body mass index, BMI = Weight (Kg) ÷ Height2 (m2); FEV1, forced expiratory volume in one second; FVC, forced vital capacity; PEF, peak expiratory flow; HBP, high blood pressure; CHD, coronary heart disease; GERD, gastroesophageal reflux disease; FeNO, exhaled nitric oxide fraction; ICS, inhaled corticosteroids; AHI, apnea-hypopnea index; ODI, oxygen desaturation index; REM, rapid eye movement sleep; TST, total sleep time; SaO2, arterial oxygen saturation.