Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 3;7:7219. doi: 10.1038/s41598-017-07575-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

miR-23 is a putative regulator of TrxR1 expression during skeletal muscle differentiation. (a) RT-qPCR analysis showing the relative expression of TrxR1 mRNA in proliferating (GM) versus differentiating (DM) C2C12 cells collected at 1, 2, 3 and 5 days. Data were normalised to Cyclophilin A expression and represented as mean ± SEM of three independent experiments. (b) Relative expression of TrxR1 mRNA in proliferating (GM) versus differentiating (DM) satellite cells, measured by RT-qPCR and normalized to GAPDH expression. (c) Putative miR-23a and b binding sites in the 3′ UTR of TrxR1 mRNA. (d) RT-qPCR analysis displaying miR-23a andmiR-23b expression (normalized to U6 snoRNA) in C2C12 proliferating (GM) versus differentiating (DM) cells. Data are exposed as mean ± SEM of three experiments. The normalised GM values of each miRNA were set = 1.