Figure 2.
Uptake of 111In-exendin by islet transplants is in linear correlation with transplant size. (A) SPECT imaging detected the grafts initially transplanted with 50, 100, 200, 400 or 800 islets with high sensitivity, 4 weeks after transplantation (white arrows). (B) 111In-exendin uptake (expressed in kilobecquerels, kBq) was dependent on transplant size (n = 4–5). Data are shown as means ± SEM (n = 5). (C) SPECT signal (expressed in kBq) correlated linearly with graft insulin-positive volume (µm3). (Pearson r = 0.89, 95% confidence interval shown as a dotted line).