Table 2. Histopathological results according to study groups (n=38) and distribution of high- and low-grade lesions in the MNU-only and MNU+O3 groups.
| MNU only (n=11) |
MNU+O3 (n=12) |
O3 only (n=10) |
Sham (n=5) | |
|---|---|---|---|---|
| Normal urothelium, n (%) | 0 (0) | 2 (16.7) | 9 (90) | 5 (100) |
| Preneoplastic lesions | ||||
| Hyperplasia, n (%) | 1 (9.1) | 1 (8.3) | 1 (10) | 0 (0) |
| Dysplasia / atypia (low-grade intraepithelial neoplasia), n (%) | 3 (27.3) | 2 (16.7) | 0 (0) | 0 (0) |
| NMIBC | ||||
| High-grade intraepithelial neoplasia (CIS), n (%) | 3 (27.3) | 1 (8.3) | 0 (0) | 0 (0) |
| Low-grade pTa papillary urothelial cancer, n (%) | 2 (18.2) | 3 (25.0) | 0 (0) | 0 (0) |
| Low-grade pT1 papillary urothelial cancer, n (%) | 2 (18.2) | 3 (25.0) | 0 (0) | 0 (0) |
| High-grade pT1 papillary urothelial cancer, n (%) | 1 (9.1) | 0 (0) | 0 (0) | 0 (0) |
| All High-grade urothelial lesions (CIS, pTa, or pT1) | 4 (36.4) | 1 (8.3) | 0 (0) | 0 (0) |