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Effect of cocaine [100 nM; (A)], amphetamine [10 µM; (A)], JWH-018 [100 nM and 1 µM, (B)], and AKB48 [100 nM and 1 µM, (C)] on spontaneous [3H]-dopamine (DA) efflux from striatal synaptosomes obtained from CD-1 mice. Data are expressed as percentage of basal values and represent the mean ± SEM of 4–6 repetitions for each treatment. ***p < 0.001 significantly different from the respective control group according to ANOVA followed by Newman–Keuls test for multiple comparisons.
