Table 1.
Minimum inhibitory concentration and presence of antibiotic resistance genes of methicillin resistant and susceptible S. epidermidis isolated from the infected eye and healthy conjunctiva.
| Antibiotics | Resistance gene marker | No. of strains (%) positive for antibiotic resistance genes | No. of strains showing MIC value of antibiotics (mg/L) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MRSE | MSSE | Total | 0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | >64 | ||
| Oxacillin | mecA | 35 (67%) | 0 (0%) | 35 (67%) | 0 | 4 | 4 | 3 | 0 | 0 | 2 | 0 | 1 | 0 | 21 |
| Penicillin | blaZ | 32 (62%) | 18 (35%) | 50 (96%) | 0 | 0 | 0 | 12 | 0 | 5 | 11 | 3 | 2 | 6 | 11 |
| Chloramphenicol | catpC223 | 2 (4%) | 2 (4%) | 4 (8%) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 |
| catpC221 | 33 (63%) | 14 (27%) | 47 (90%) | 0 | 0 | 0 | 0 | 0 | 5 | 7 | 16 | 4 | 3 | 12 | |
| catpC223 + catpC221 | 2 (4%) | 2 (4%) | 4 (8%) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | |
| Erythromycin | ermC | 25 (48%) | 15 (28%) | 40 (76.9%) | 2 | 3 | 1 | 4 | 3 | 0 | 1 | 1 | 3 | 0 | 22 |
| msrA | 14 (27%) | 4 (8%) | 18 (35%) | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 3 | 0 | 12 | |
| ermC + msrA | 13 (25%) | 4 (8%) | 17 (33%) | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 3 | 0 | 11 | |
| Clindamycin | mphC | 16 (31%) | 9 (17%) | 25 (48%) | 15 | 1 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 3 |
| Gentamicin | aac6′-aph2′ | 32 (62%) | 14 (27%) | 47 (90%) | 28 | 3 | 1 | 3 | 0 | 3 | 0 | 0 | 4 | 1 | 4 |
| aph3′ | 18 (35%) | 7 (13%) | 25 (48%) | 6 | 5 | 0 | 1 | 1 | 4 | 0 | 0 | 4 | 1 | 3 | |
| aac6′-aph2′+ aph3′ | 17 (33%) | 5 (10%) | 22 (42%) | 6 | 4 | 0 | 1 | 1 | 3 | 0 | 0 | 3 | 1 | 3 | |
| Tetracycline | tetK | 32 (62%) | 15 (29%) | 47 (98%) | 0 | 0 | 0 | 4 | 6 | 0 | 4 | 1 | 5 | 21 | 6 |
Resistant: Bold; Intermediate: Bold italic; Sensitive: Normal.