Table. Immunohistochemical Results in This Series of Histiocytoid Sweet Syndrome.
| Case | Histopathology | CD163/ MPOa |
CD163 | MPO | MNDA/ MPOa |
MNDA | MPO | MNDA/ CD163a |
MNDA | CD163 | MNDA/ CD14 |
MNDA | CD14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | HSS typical pattern. Mitoses | − | + | +++ | +++ | + | + | +/− | +++ | + | + | +++ | ++ |
| 2 | Scant edema | − | + | +++ | ++ | ++ | + | + | +++ | + | ++ | +++ | + |
| 3 | HSS typical pattern | − | + | +++ | +++ | +/− | +/− | +/− | +++ | +/− | +/− | +++ | + |
| 4 | Scant edema. Perivascular and interstitial infiltrate | − | +/− | +++ | ++ | + | + | + | +++ | +/− | ++ | +++ | + |
| 5 | Prominent edema. Interstitial infiltrate | − | +/− | +++ | +++ | + | +/− | +++ | +/− | +/− | +++ | + | +/− |
| 6 | Scant edema. Interstitial infiltrate | − | +/− | +++ | +++ | + | +/− | + | +++ | + | +++ | +/− | +/− |
| 7 | Focal edema. Superficial and deep infiltrate | − | + | ++ | +++ | + | +/− | + | +++ | + | + | +++ | + |
| 8 | HSS typical pattern | − | + | +++ | +++ | + | +/− | − | +++ | +/− | + | ++ | − |
| 9 | Scant edema. Superficial and deep perivascular infiltrate | − | + | +++ | +++ | +/− | +/− | +/− | +++ | +/− | ++ | + | +/− |
| 10 | HSS typical pattern | − | + | +++ | +++ | +/− | +/− | +/− | +++ | + | + | ++ | +/− |
| 11 | HSS typical pattern | − | + | +++ | +++ | +/− | +/− | +/− | +++ | +/− | +/− | +++ | +/− |
| 12 | Diffuse interstitial infiltrate with septal involvement of the subcutis. Mucin deposits | − | +/− | +++ | +++ | +/− | + | +++ | + | +/− | +/− | +++ | +/− |
| 13 | Diffuse interstitial infiltrate with septal involvement of the subcutis. Mucin deposits | − | +/− | +++ | +++ | +/− | +/− | +++ | +/− | +/− | +/− | +++ | + |
| 14 | HSS typical pattern | − | + | +++ | +++ | + | +/− | + | +++ | + | + | +++ | +/− |
| 15 | HSS typical pattern | +/− | + | +++ | +++ | +/− | − | +/− | +++ | + | + | +++ | − |
| 16 | HSS typical pattern | +/− | + | +++ | +++ | +/− | +/− | +/− | +++ | + | + | +++ | + |
| 17 | HSS typical pattern | − | + | +++ | +++ | + | +/− | +/− | +++ | + | + | +++ | − |
| 18 | HSS typical pattern and neutrophils | +/− | + | +++ | +++ | + | + | +/− | +++ | +/− | +/− | +++ | +/− |
| 19 | Interstitial pattern | − | ++ | + | +++ | + | + | + | ++ | +++ | +++ | ++ | +/− |
| 20 | HSS typical pattern | − | + | +++ | +++ | + | +/− | +/− | +++ | + | + | +++ | +/− |
| 21 | HSS typical pattern | +/− | + | +++ | +++ | ++ | − | +/− | +++ | +/− | +/− | +++ | +/− |
| 22 | Focal edema. Scattered neutrophils | +/− | + | +++ | +++ | + | − | − | +++ | +/− | +/− | +++ | − |
| 23 | HSS typical pattern | +/− | +/− | +++ | +++ | +/− | + | − | +++ | +/− | +/− | +++ | − |
| 24 | HSS typical pattern | − | +/− | +++ | +++ | +/− | + | − | +++ | +/− | +/− | +++ | − |
| 25 | HSS typical pattern | − | + | +++ | +++ | + | +/− | + | +++ | +/− | +/− | ++ | +/− |
| 26 | HSS typical pattern | − | +/− | +++ | +++ | +/− | +/− | +/− | +++ | + | + | +++ | +/− |
| 27 | HSS typical pattern | − | +/− | +++ | +++ | + | +/− | + | +++ | +/− | +/− | +++ | +/− |
| 28 | HSS typical pattern | − | + | +++ | +++ | +/− | +/− | +++ | +/− | +/− | +/− | +++ | +/− |
| 29 | HSS typical pattern | − | + | +++ | +++ | + | +/− | + | +++ | +/− | +/− | +++ | +/− |
| 30 | HSS typical pattern | − | + | +++ | +++ | + | +/− | − | +++ | + | + | +++ | +/− |
| 31 | HSS typical pattern | − | +/− | +++ | +++ | +/− | +/− | +/− | +++ | +/− | +/− | +++ | + |
| 32 | HSS typical pattern | − | +/− | +++ | +++ | +/− | +/− | +/− | +++ | +/− | +/− | +++ | + |
| 33 | HSS typical pattern | − | + | +++ | +++ | +/− | +/− | +/− | +++ | +/− | +/− | +++ | + |
Abbreviations: HSS, histiocytoid Sweet syndrome; MNDA, myeloid nuclear differentiation antigen; MPO, myeloperoxidase.
a
One of the most important double immunostains.