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. 2017 Jul 3;177(7):955–965. doi: 10.1001/jamainternmed.2017.1442

Table 3. Multivariable Regression for All-Cause Mortality by Age Group and for Coronary Heart Disease (CHD) Events by Age Group.

Variable 65-74 y ≥75 y Total
HR (95% CI) P Value HR (95% CI) P Value HR (95% CI) P Value
Multivariable Regression for All-Cause Mortality by Age Group
Pravastatin 1.05 (0.82-1.33) .72 1.36 (0.98-1.89) .06 1.15 (0.94-1.39) .17
Age 1.06 (1.01-1.10) .01 1.11 (1.06-1.15) <.01 1.08 (1.06-1.10) <.01
Female 0.83 (0.65-1.07) .16 0.53 (0.38-0.74) <.01 0.71 (0.58-0.87) <.01
Systolic blood pressure 1.01 (1.00-1.02) .01 1.01 (1.00-1.02) .11 1.01 (1.00-1.02) <.01
Diastolic blood pressure 0.99 (0.98-1.01) .37 1.00 (0.98-1.02) .90 1.00 (0.99-1.01) .52
Aspirin use 1.03 (0.77-1.36) .86 0.86 (0.59-1.24) .42 0.97 (0.77-1.21) .78
Body mass index 1.00 (0.98-1.02) .90 0.99 (0.95-1.02) .44 1.00 (0.98-1.02) .98
Black race/ethnicity 1.04 (0.81-1.33) .76 1.15 (0.82-1.60) .41 1.08 (0.88-1.31) .47
Current cigarette smoker 1.90 (1.43-2.53) <.01 1.49 (0.91-2.45) .11 1.75 (1.37-2.24) <.01
Type 2 diabetes 1.74 (1.32-2.29) <.01 1.66 (1.17-2.35) <.01 1.66 (1.34-2.05) <.01
Multivariable Regression for CHD Events by Age Group
Pravastatin 0.85 (0.63-1.16) .31 0.70 (0.42-1.15) .16 0.80 (0.62-1.04) .09
Age 1.02 (0.96-1.08) .48 1.05 (0.99-1.12) .13 1.03 (1.01-1.06) .01
Female 0.77 (0.56-1.06) .11 0.46 (0.27-0.77) <.01 0.65 (0.50-0.86) <.01
Systolic blood pressure 1.01 (1.00-1.02) .06 1.01 (0.99-1.02) .51 1.01 (1.00-1.02) .06
Diastolic blood pressure 1.00 (0.98-1.02) .75 1.00 (0.98-1.03) .86 1.00 (0.98-1.01) .83
Aspirin use 1.05 (0.73-1.49) .80 1.52 (0.92-2.51) .11 1.21 (0.91-1.61) .20
Body mass index 1.00 (0.97-1.02) .75 0.95 (0.90-1.01) .10 0.99 (0.96-1.01) .29
Black race/ethnicity 0.93 (0.68-1.28) .66 0.79 (0.46-1.35) .39 0.89 (0.68-1.17) .40
Current cigarette smoker 1.49 (1.02-2.17) .04 0.95 (0.41-2.16) .89 1.31 (0.93-1.84) .13
Type 2 diabetes 2.13 (1.49-3.04) <.01 1.30 (0.78-2.18) .32 1.80 (1.35-2.40) <.01

Abbreviation: HR, hazard ratio for pravastatin sodium vs usual care.