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. 2017 Jul 6;56(30):3972–3982. doi: 10.1021/acs.biochem.7b00153

Figure 3.

Figure 3

Crystal structures of fragments NV1 and NV2 binding to 14-3-3. (a) NV1 (yellow sticks) and (b) NV2 (magenta sticks) binding to 14-3-3σ (gray surface). The final 2FoFc electron density map (contoured at 1.0σ) is shown as blue mesh. 14-3-3σ monomer (gray surface) in complex with (c) TAZ (residues 87–95, orange sticks) and NV1 (yellow spheres) or (d) NV2 (magenta spheres). Detailed view of the 14-3-3 residues in the binding site of (e) NV1 and (f) NV2.