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. 2017 Jul 6;56(30):3972–3982. doi: 10.1021/acs.biochem.7b00153

Figure 6.

Figure 6

Position of the secondary binding sites of NV1 and NV2 in relation to the 14-3-3ζ/AANAT complex. (a) Overview of the complex of a 14-3-3 dimer (gray surface) bound to two AANAT monomers (orange surface) (PDB entry 1IB1). (b) Superimposition of the 14-3-3 structure with NV1 (yellow spheres and sticks) and NV2 (magenta spheres and sticks), with one monomer of AANAT (orange cartoon and semitransparent surface) bound to one monomer of 14-3-3ζ. (c) Detailed view of Glu43 of AANAT binding in the vicinity of the NV1 pocket in 14-3-3.