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. 2016 Aug 4;7(8):e186. doi: 10.1038/ctg.2016.43

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Copyright © 2016 American College of Gastroenterology

Clinical and Translational Gastroenterology is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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(a) Study design. (b) Gut microbiota diversity (represented as Shannon Index) based on the sequence data of bacterial 16S rRNA genes. Results are presented as box- and whisker plots showing the smallest observation, lower quartile, median, upper quartile and largest observation; P-values are calculated between time points as indicated by lines. ***P<0.001. (c) Principal component analysis (unconstrained) of fecal microbial communities. On the horizontal axis is Principal Component 1 and on the vertical axis Principal Component 2 with their corresponding percentages of explained variance. White bars or circles: day 0, black: day 8, gray: week 7.