Table 2.
Common differentially expressed miRNAs with ≥2-fold changes and p < 0.05 in FET placentae
| Fold change | p value | |||||||
|---|---|---|---|---|---|---|---|---|
| miRNA | FET vs SP | FET vs ET | ET vs SP | FET vs SP | FET vs ET | ET vs SP | Imprinted domain | |
| Upregulated | hsa-miR-1273e | 3.74 | 2.26 | 1.65 | 8.44E-04 | 5.19E-03 | 4.09E-01 | − |
| hsa-miR-197-5p | 2.13 | 2.11 | 1.01 | 3.20E-02 | 3.33E-02 | 1.00E + 00 | − | |
| hsa-miR-30c-1-3p | 3.19 | 2.02 | 1.58 | 5.21E-04 | 4.26E-03 | 2.97E-01 | − | |
| hsa-miR-4459 | 2.85 | 2.31 | 1.23 | 5.44E-03 | 1.21E-02 | 8.54E-01 | − | |
| hsa-miR-4481 | 3.00 | 2.06 | 1.46 | 9.52E-04 | 5.28E-03 | 4.51E-01 | − | |
| hsa-miR-4530 | 2.56 | 2.10 | 1.22 | 2.12E-03 | 5.55E-03 | 7.78E-01 | − | |
| hsa-miR-4697-5p | 2.95 | 2.26 | 1.30 | 9.89E-04 | 3.09E-03 | 6.83E-01 | − | |
| hsa-miR-4721 | 2.98 | 2.22 | 1.34 | 1.40E-02 | 3.68E-02 | 8.09E-01 | − | |
| hsa-miR-5006-5p | 2.84 | 2.20 | 1.29 | 9.08E-04 | 2.96E-03 | 6.61E-01 | − | |
| hsa-miR-513c-5p | 2.60 | 2.23 | 1.17 | 1.38E-02 | 2.49E-02 | 9.23E-01 | − | |
| hsa-miR-5703 | 2.71 | 2.10 | 1.29 | 1.87E-02 | 4.60E-02 | 8.33E-01 | − | |
| hsa-miR-575 | 3.63 | 2.67 | 1.36 | 3.45E-03 | 8.49E-03 | 8.12E-01 | − | |
| hsa-miR-5787 | 3.43 | 2.06 | 1.67 | 4.06E-03 | 2.53E-02 | 4.68E-01 | − | |
| hsa-miR-622 | 3.05 | 2.07 | 1.48 | 1.72E-03 | 9.07E-03 | 4.95E-01 | − | |
| hsa-miR-630 | 2.69 | 2.23 | 1.21 | 1.50E-02 | 2.94E-02 | 9.01E-01 | − | |
| hsa-miR-6893-5p | 2.49 | 2.05 | 1.21 | 3.14E-03 | 8.14E-03 | 7.90E-01 | − | |
| hsa-miR-7150 | 3.53 | 2.16 | 1.64 | 2.53E-04 | 2.01E-03 | 2.69E-01 | − | |
| hsa-miR-8072 | 2.92 | 2.15 | 1.36 | 1.77E-04 | 8.19E-04 | 4.32E-01 | − | |
| Downregulated | hsa-miR-10a-5p | 0.47 | 0.46 | 1.03 | 9.83E-03 | 7.11E-03 | 9.74E-01 | − |
| hsa-miR-125a-5p | 0.47 | 0.46 | 1.01 | 1.61E-02 | 1.41E-02 | 9.96E-01 | − | |
| hsa-miR-1260b | 0.46 | 0.48 | 0.95 | 6.70E-03 | 1.14E-02 | 9.31E-01 | − | |
| hsa-miR-130a-3p | 0.46 | 0.48 | 0.94 | 9.96E-03 | 1.87E-02 | 9.10E-01 | − | |
| hsa-miR-148b-3p | 0.47 | 0.49 | 0.97 | 3.69E-02 | 4.78E-02 | 9.85E-01 | − | |
| hsa-miR-149-5p | 0.41 | 0.34 | 1.20 | 2.66E-02 | 5.05E-03 | 5.35E-01 | − | |
| hsa-miR-193b-3p | 0.25 | 0.37 | 0.69 | 2.08E-03 | 4.29E-02 | 1.57E-01 | − | |
| hsa-miR-224-3p | 0.47 | 0.49 | 0.96 | 2.73E-02 | 4.02E-02 | 9.67E-01 | − | |
| hsa-miR-331-3p | 0.33 | 0.37 | 0.89 | 1.09E-02 | 2.72E-02 | 8.23E-01 | − | |
| hsa-miR-365a-3p | 0.30 | 0.41 | 0.74 | 1.30E-03 | 2.17E-02 | 1.78E-01 | − | |
| hsa-miR-374b-5p | 0.46 | 0.49 | 0.94 | 1.96E-02 | 3.44E-02 | 9.31E-01 | − | |
| hsa-miR-423-5p | 0.42 | 0.46 | 0.91 | 4.87E-03 | 1.27E-02 | 7.98E-01 | − | |
| hsa-miR-487b-3p | 0.33 | 0.39 | 0.85 | 1.62E-03 | 8.38E-03 | 5.01E-01 | C14MC | |
| hsa-miR-495-3p | 0.35 | 0.39 | 0.89 | 1.02E-03 | 3.61E-03 | 6.31E-01 | C14MC | |
| hsa-miR-518b | 0.32 | 0.38 | 0.83 | 2.65E-03 | 1.49E-02 | 4.90E-01 | C19MC | |
| hsa-miR-518f-3p | 0.38 | 0.48 | 0.79 | 1.08E-03 | 1.46E-02 | 2.09E-01 | C19MC | |
| hsa-miR-520a-5p | 0.48 | 0.50 | 0.97 | 7.20E-03 | 1.08E-02 | 9.60E-01 | C19MC | |
| hsa-miR-543 | 0.36 | 0.34 | 1.06 | 2.72E-02 | 1.76E-02 | 9.57E-01 | C14MC | |
| hsa-miR-574-3p | 0.24 | 0.26 | 0.95 | 1.48E-02 | 2.13E-02 | 9.70E-01 | − | |
| hsa-miR-7977 | 0.32 | 0.39 | 0.83 | 2.51E-03 | 1.41E-02 | 4.87E-01 | − | |
| hsa-miR-99a-5p | 0.30 | 0.41 | 0.73 | 9.95E-04 | 1.96E-02 | 1.45E-01 | − | |
Letters in italics indicate miRNAs confirmed by qRT-PCR in this study