Table 4.
Top 20 KEGG pathways related to predicted target genes by four miRNAs
| Pathway | Gene count | p value | Corrected p value |
|---|---|---|---|
| Axon guidance | 46 | 1.73E-08 | 3.16E-06 |
| Neurotrophin signaling pathway | 42 | 4.05E-07 | 3.70E-05 |
| MAPK signaling pathway | 72 | 5.70E-07 | 3.48E-05 |
| GnRH signaling pathway | 35 | 1.15E-06 | 5.28E-05 |
| Melanogenesis | 35 | 1.51E-06 | 5.52E-05 |
| Wnt signaling pathway | 46 | 2.94E-06 | 8.97E-05 |
| Pathways in cancer | 79 | 1.67E-05 | 4.37E-04 |
| Gap junction | 30 | 2.80E-05 | 6.41E-04 |
| Pancreatic cancer | 26 | 2.99E-05 | 6.07E-04 |
| Insulin signaling pathway | 40 | 3.00E-05 | 5.49E-04 |
| Focal adhesion | 53 | 4.47E-05 | 7.44E-04 |
| VEGF signaling pathway | 26 | 6.52E-05 | 9.93E-04 |
| Endocytosis | 49 | 7.02E-05 | 9.88E-04 |
| Long-term potentiation | 24 | 9.85E-05 | 1.29E-03 |
| Long-term depression | 24 | 1.27E-04 | 1.55E-03 |
| ErbB signaling pathway | 28 | 1.35E-04 | 1.54E-03 |
| Colorectal cancer | 27 | 1.88E-04 | 2.02E-03 |
| SNARE interactions in vesicular transport | 16 | 2.37E-04 | 2.41E-03 |
| Phosphatidylinositol signaling system | 24 | 4.08E-04 | 3.92E-03 |
| Glioma | 21 | 7.09E-04 | 6.47E-03 |