Table 1.
Inhibitory effects of PFE, Rib and Fin on 5α-reductase activity in rat prostate
Group | 5α-reductase inhibition (%) |
---|---|
PFE | 31.8 ± 15.0 |
Rib | 89.1 ± 18.1 |
Fin | 94.3 ± 46.1 |
The effect of PFE (PFE-treated group) on rat prostatic 5α-reductase was tested at a concentration of 0.25 mg/mL. A nonsteroidal-positive control with Rib (riboflavin-treated group) of 1000 μM and a steroidal-positive control with Fin (finasteride-treated group) of 100 nM. Values are means of results from two different experiments