Figure 4.

Additional applications of DNA origami nanocarriers. (a) Doxorubicin (Dox)‐loaded DNA origami tubes and triangles exhibited drug resistance circumvention when treated with resistant MCF‐7 cells. Reproduced from Jiang (2012), with permission from [American Chemical Society].(45 ) (b) Gold nanorod (AuNR)‐functionalized DNA origami tubes and triangles used in photothermal dynamic therapy showed lower percentage cell viability of tumor cells in mice. Reproduced from Jiang et al. (2015), with permission from [John Wiley and Sons].50 DO‐GNR, DNA origami‐gold nanorod; dsDNA, double‐stranded DNA; GNR, gold nanorod; IR, infrared.