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. 2016 Jul 21;7(7):e184. doi: 10.1038/ctg.2016.40

Table 2. Clinical features of patients and controls.

  Cancer set
Control set
  n =20 Average BARHL2 gene methylation (%) P -value n =10 Average BARHL2 gene methylation (%) P -value
Age   72.3±7.0 36.4±14.0 0.28   62.7±13.3 7.8±2.7 0.83
Male 12 71.1±8.2 38.8±13.2   7 64.0±13.1 7.6±3.0  
Female 8 74.0±4.8 32.8±15.2   3 62.0±16.1 9.2±1.8  
Histology (adenocarcinoma)       0.9        
 Well differentiated 7   34.6±16.0          
 Moderately differentiated 6   37.2±17.8          
 Poorly differentiated 7   37.6±9.6          
Stage       0.71        
 I 10   35.5±14.2          
 II/III/IV 10   37.3±14.5          
Lymphnode metastasis       0.4        
 Positive 8   38.6±15.9          
 Negative 12   34.9±13.1          
Helicobacter pylori infection       0.68       0.91
 Positive 14   36.1±13.0   5   7.7±3.3  
 Negative 6   37.0±17.4   5   8.5±2.3  
Atrophy       NA       0.91
 Non-atrophy 0   NA   5   8.5±2.3  
 Closed type 5   33.4±16.8 0.76 2   7.3±2.1 0.8
 Open type 15   37.4±13.4   3   8.0±4.4  

BARHL2, BarH-like 2 homeobox protein; NA, not applicable.

Cancer n=20 and non-cancer n=10.