Table 2. Clinical features of patients and controls.
Cancer set
|
Control set
|
|||||||
---|---|---|---|---|---|---|---|---|
n =20 | Average | BARHL2 gene methylation (%) | P -value | n =10 | Average | BARHL2 gene methylation (%) | P -value | |
Age | 72.3±7.0 | 36.4±14.0 | 0.28 | 62.7±13.3 | 7.8±2.7 | 0.83 | ||
Male | 12 | 71.1±8.2 | 38.8±13.2 | 7 | 64.0±13.1 | 7.6±3.0 | ||
Female | 8 | 74.0±4.8 | 32.8±15.2 | 3 | 62.0±16.1 | 9.2±1.8 | ||
Histology (adenocarcinoma) | 0.9 | |||||||
Well differentiated | 7 | 34.6±16.0 | ||||||
Moderately differentiated | 6 | 37.2±17.8 | ||||||
Poorly differentiated | 7 | 37.6±9.6 | ||||||
Stage | 0.71 | |||||||
I | 10 | 35.5±14.2 | ||||||
II/III/IV | 10 | 37.3±14.5 | ||||||
Lymphnode metastasis | 0.4 | |||||||
Positive | 8 | 38.6±15.9 | ||||||
Negative | 12 | 34.9±13.1 | ||||||
Helicobacter pylori infection | 0.68 | 0.91 | ||||||
Positive | 14 | 36.1±13.0 | 5 | 7.7±3.3 | ||||
Negative | 6 | 37.0±17.4 | 5 | 8.5±2.3 | ||||
Atrophy | NA | 0.91 | ||||||
Non-atrophy | 0 | NA | 5 | 8.5±2.3 | ||||
Closed type | 5 | 33.4±16.8 | 0.76 | 2 | 7.3±2.1 | 0.8 | ||
Open type | 15 | 37.4±13.4 | 3 | 8.0±4.4 |
BARHL2, BarH-like 2 homeobox protein; NA, not applicable.
Cancer n=20 and non-cancer n=10.