Figure 4.

The Sambucus nigra agglutinin/d‐galactose, N‐acetyl galactosamine (SNA/GalNAc‐L) binding ratio of the native immunoglobulin (Ig)G complexes complexes changes in dependency of the therapy. (a) The SNA/GalNAc‐L reactivity ratio of native IgG complexes discriminates patients with rheumatoid arthritis (RA) before and after therapy. A contingency table analysis was performed using χ² test and Yates’ correction. (b) The SNA/GalNAc‐L reactivity ratio increases or remains constant in course of treatment in 26 of 30 cases. Only four of 30 patients present a slight decrease in SNA/GalNAc‐L binding ratio after the inclusion visit (P < 0·0001). Shown are SNA/GalNAc‐L ratio values and P‐values presented after post‐test correction.