Table 1.
HPV Infection Frequency in normal epithelium, preneoplastic and neoplastics lesions of the cervix
| HPV Status | NORMAL | LSIL | HSIL | SCC | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % Over Total Number of cases | % Over Total Number of SI or MI cases | n | % Over Total Number of cases | % Over Total Number of SI or MI cases | n | % Over Total Number of cases | % Over Total Number of SI or MI cases | n | % Over Total Number of cases | % Over Total Number of SI or MI cases | |
| HPV negative | 68 | 89.5 | 0.0 | 41 | 16.5 | 0.0 | 79 | 12.4 | 0.0 | 1 | 4.2 | 0.0 |
| Single Infection | 6 | 7.9 | 100.0 | 142 | 57.0 | 100.0 | 425 | 66.8 | 100.0 | 21 | 87.5 | 100.0 |
| HPV 6 | 0 | 0.0 | 0.0 | 0 | 0.0 | 0.0 | 1 | 0.2 | 0.2 | 0 | 0.0 | 0.0 |
| HPV 11 | 1 | 1.3 | 16.7 | 5 | 2.0 | 3.5 | 3 | 0.5 | 0.7 | 0 | 0.0 | 0.0 |
| HPV 16 | 0 | 0.0 | 0.0 | 67 | 26.9 | 47.2 | 249 | 39.2 | 58.6 | 13 | 54.2 | 61.9 |
| HPV 18 | 0 | 0.0 | 0.0 | 10 | 4.0 | 7.0 | 30 | 4.7 | 7.1 | 4 | 16.7 | 19.0 |
| HPV 26 | 0 | 0.0 | 0.0 | 2 | 0.8 | 1.4 | 5 | 0.8 | 1.2 | 0 | 0.0 | 0.0 |
| HPV 31 | 1 | 1.3 | 16.7 | 2 | 0.8 | 1.4 | 32 | 5.0 | 7.5 | 0 | 0.0 | 0.0 |
| HPV 33 | 0 | 0.0 | 0.0 | 2 | 0.8 | 1.4 | 12 | 1.9 | 2.8 | 0 | 0.0 | 0.0 |
| HPV 35 | 0 | 0.0 | 0.0 | 6 | 2.4 | 4.2 | 7 | 1.1 | 1.6 | 0 | 0.0 | 0.0 |
| HPV 39 | 0 | 0.0 | 0.0 | 2 | 0.8 | 1.4 | 1 | 0.2 | 0.2 | 1 | 4.2 | 4.8 |
| HPV 42 | 1 | 1.3 | 16.7 | 0 | 0.0 | 0.0 | 2 | 0.3 | 0.5 | 0 | 0.0 | 0.0 |
| HPV 44 | 0 | 0.0 | 0.0 | 1 | 0.4 | 0.7 | 1 | 0.2 | 0.2 | 0 | 0.0 | 0.0 |
| HPV 45 | 2 | 2.6 | 33.3 | 10 | 4.0 | 7.0 | 20 | 3.1 | 4.7 | 1 | 4.2 | 4.8 |
| HPV 51 | 0 | 0.0 | 0.0 | 8 | 3.2 | 5.6 | 4 | 0.6 | 0.9 | 0 | 0.0 | 0.0 |
| HPV 52 | 0 | 0.0 | 0.0 | 5 | 2.0 | 3.5 | 8 | 1.3 | 1.9 | 0 | 0.0 | 0.0 |
| HPV 53 | 1 | 1.3 | 16.7 | 0 | 0.0 | 0.0 | 3 | 0.5 | 0.7 | 0 | 0.0 | 0.0 |
| HPV 56 | 0 | 0.0 | 0.0 | 7 | 2.8 | 4.9 | 6 | 0.9 | 1.4 | 0 | 0.0 | 0.0 |
| HPV 58 | 0 | 0.0 | 0.0 | 7 | 2.8 | 4.9 | 24 | 3.8 | 5.6 | 0 | 0.0 | 0.0 |
| HPV 59 | 0 | 0.0 | 0.0 | 0 | 0.0 | 0.0 | 1 | 0.2 | 0.2 | 0 | 0.0 | 0.0 |
| HPV 66 | 0 | 0.0 | 0.0 | 7 | 2.8 | 4.9 | 9 | 1.4 | 2.1 | 1 | 4.2 | 4.8 |
| HPV 68 | 0 | 0.0 | 0.0 | 0 | 0.0 | 0.0 | 2 | 0.3 | 0.5 | 1 | 4.2 | 4.8 |
| HPV 70 | 0 | 0.0 | 0.0 | 0 | 0.0 | 0.0 | 2 | 0.3 | 0.5 | 0 | 0.0 | 0.0 |
| HPV 81 | 0 | 0.0 | 0.0 | 1 | 0.4 | 0.7 | 3 | 0.5 | 0.7 | 0 | 0.0 | 0.0 |
| Multiple Infection | 2 | 2.6 | 100.0 | 66 | 26.5 | 100.0 | 132 | 20.8 | 100.0 | 2 | 8.3 | 100.0 |
| HPV 16/HRs | 1 | 1.3 | 50.0 | 17 | 6.8 | 25.8 | 39 | 6.1 | 29.5 | 1 | 4.2 | 50.0 |
| HPV 16/LRs | 0 | 0.0 | 0.0 | 6 | 2.4 | 9.1 | 7 | 1.1 | 5.3 | 0 | 0.0 | 0.0 |
| HPV 18/HRs | 0 | 0.0 | 0.0 | 7 | 2.8 | 10.6 | 12 | 1.9 | 9.1 | 0 | 0.0 | 0.0 |
| HPV 16/18 | 1 | 1.3 | 50.0 | 14 | 5.6 | 21.2 | 19 | 3.0 | 14.4 | 1 | 4.2 | 50.0 |
| HPV 16/18/HRs | 0 | 0.0 | 0.0 | 9 | 3.6 | 13.6 | 11 | 1.7 | 8.3 | 0 | 0.0 | 0.0 |
| HRs-HPV | 0 | 0.0 | 0.0 | 6 | 2.4 | 9.1 | 24 | 3.8 | 18.2 | 0 | 0.0 | 0.0 |
| HRs/LRs-HPV | 0 | 0.0 | 0.0 | 3 | 1.2 | 4.5 | 10 | 1.6 | 7.6 | 0 | 0.0 | 0.0 |
| Others MI | 0 | 0.0 | 0.0 | 4 | 1.6 | 6.1 | 10 | 1.6 | 7.6 | 0 | 0.0 | 0.0 |
| TOTAL | 76 | 100.0 | - | 249 | 100.0 | - | 636 | 100.0 | - | 24 | 100.0 | - |
HPV Human papillomavirus, LSIL Low-grade squamous intraepithelial lesions, HSIL High-grade squamous intraepithelial lesions, SCC Squamous Cervical Carcinoma, SI Single Infections, MI Multiple Infections, HR-HPV High risk Human papillomavirus, LR-HPV Low risk Human papillomavirus