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Effect of tanshinone IIA on OGD/R-caused autophagy in HT-22 cells. Tanshinone IIA inhibited significantly inhibited the expression of Bax and LC3 II but promoted expression of p85, mTOR and Akt (The main components of PI3K/Akt/mTOR pathway). Representative photographs of fluorescence for the autophagy marker LC 3II (A). Western-blots analysis (B) Scale bar represents 50 µm.
