Table 1.

Description of the data set in terms of studies per treatment and the sample sizes, on day 28

Treatments	Studies per treatment arm	Studies tested the trt with AL	Total sample size	Nbr of ACPR	% of ACPR
AL	63	–	12,981	11,426	88
AQSP	12	7	2681	1731	64.56
ASAQ	42	31	8254	7402	89.6
ASAQCPH	1	1	54	47	87.03
ASATPG	1	0a	100	95	95
ASCD	4	4	1591	1326	83.3
ASMQ	6	5	843	800	94.89
ASNAPH	2	2	147	144	97.95
ASPY	2	2	1204	1105	91.77
ASSMP	4	3	1545	1461	94.5
ASSP	11	3	1752	1593	91
DHAP	22	18	6182	4969	80.3
DHAPT	1	1	212	204	96.2

Data were extracted for all studies. The combination AL was the most frequently evaluated drug combination within the data. Few studies tested novel combinations. There was no study comparing ASATPG directly to AL

Nbr number, trt treatment, ACPR adequate clinical and parasitological response corrected by PCR