Table 5.
Rank probabilities | |||||
---|---|---|---|---|---|
Treatments | Odds ratios | 95% CrI | Rank 1 | Rank 2 | Rank 3 |
AL | – | – | 0 | 10−5 | 10−4 |
AQSP | 0.87 | 0.50–1.51 | 0.0004 | 10−4 | 0.005 |
ASAQ | 1.12 | 0.82–1.54 | 0.00 | 10−4 | 0.007 |
ASMQ | 1.20 | 0.52–2.80 | 0.0016 | 0.05 | 0.08 |
ASSP | 1.35 | 0.71–2.58 | 0.01 | 0.05 | 0.10 |
DHAP | 1.92 | 1.29–2.83 | 0.04 | 0.20 | 0.30 |
A total of 76 studies were analysed using the random effect model 2 under the hypothesis of consistency. Treatments were numbered as the first six combinations. Posterior distributions of odds ratio and 95% credible intervals (CrI) were extracted. AL was the comparator. Posterior rank probabilities are given for ranks 1, 2 and 3. In this model, DHAP was shown to be the most efficacious among the combination therapies