Table 2.
Schedule of procedures/evaluations in Acute Cohort
| Procedure/Evaluation | Baseline (prior to starting anthracycline) | Study Visits prior to each anthracycline dose | 3 months after completion of final anthracycline dose (± 4 weeks) |
12 months after completion of final anthracycline dose (± 8 weeks) |
|---|---|---|---|---|
| Informed Consent/Assent | X | |||
| Demographics | X | |||
| Height (cm) & Weight (kg) | X | X | X | X |
| Concomitant Medications | X | X | X | X |
| Medical History | X | |||
| Review of Medical Events | X | X | X | X |
| Cancer Therapy | X | X | ||
| Echocardiogram (ECHO) | X | Xa | X | |
| Genetic Sample | Obtain one sample at any time point while patient is on-study% | |||
| OPTIONAL Biomarker Sample |
X | X | X | X |
%For patients who will be having an allogeneic stem cell transplant, collect the genetic sample prior to the procedure
aECHOs will be performed prior to each dose of anthracycline when possible. If patient/parent is not agreeable to research-only ECHOs, then they will occur only at clinically indicated time points