Fig. 4.

Distribution of rabies diagnostic laboratories in Latin America and the Caribbean, their capacity and their affiliation to a Ministry of Health or Ministry of Agriculture. Color-coded countries represent total human rabies cases reported, as a reflection of testing capacity. Countries with low numbers of cases are in blue, medium in pink, and high in red. Countries with no cases reported or no data available are shown in white. Laboratory diagnostic capacity is depicted as follows: green dots for countries performing the “gold standard” direct fluorescent antibody test (DFA), filled black squares for countries performing DFA and viral typing by monoclonal antibodies and/or sequencing techniques (typing), and gold stars for countries performing DFA, viral typing and antibody titration via rapid immune fluorescent foci inhibition test (RIFFT). Countries with two icons (dot and square) represent independent diagnostic capacities for laboratories of the Ministry of Health and the Ministry of Agriculture. The locations of the icons represent the actual geographic locations of the labs. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)