Table 3.
Data (mean ± SEM) from the gait analysis, collapsed across sessions.
Measure | GD3S+/+ | GD3S−/− | ||
---|---|---|---|---|
|
|
|||
Saline | MPTP | Saline | MPTP | |
Forepaws: | ||||
Stance width (cm) | 1.70 ± 0.06 | 1.68 ± 0.09 | 1.64 ± 0.05 | 1.72 ± 0.04 |
Step angle (°) | 67.87 ± 2.13 | 66.29 ± 2.24 | 63.37 ± 1.61 | 63.54 ± 1.85 |
Stance (s) | 0.22 ± 0.01 | 0.23 ± 0.01 | 0.23 ± 0.00 | 0.23 ± 0.01 |
Stride (s) | 0.36 ± 0.01 | 0.35 ± 0.01 | 0.34 ± 0.01 | 0.34 ± 0.01 |
Swing (s) | 0.13 ± 0.01 | 0.12 ± 0.01 | 0.11 ± 0.01^ | 0.11 ± 0.00 |
Brake (s) | 0.14 ± 0.00 | 0.14 ± 0.00 | 0.13 ± 0.01 | 0.13 ± 0.00 |
Propel (s) | 0.09 ± 0.00 | 0.09 ± 0.00 | 0.09 ± 0.01 | 0.09 ± 0.01 |
Paw angle (°) | 6.87 ± 0.66 | 4.52 ± 0.47** | 5.67 ± 0.81 | 4.61 ± 0.56 |
Paw Area (cm2) | 0.45 ± 0.01 | 0.51 ± 0.02* | 0.46 ± 0.02 | 0.53 ± 0.02 |
Hindpaws: | ||||
Stance width (cm) | 2.56 ± 0.07 | 2.64 ± 0.08 | 2.58 ± 0.05 | 2.64 ± 0.05 |
Step angle (°) | 55.78 ± 1.77 | 57.23 ± 1.51 | 58.10 ± 1.25 | 58.09 ± 1.33 |
Stance (s) | 0.25 ± 0.00 | 0.25 ± 0.00 | 0.24 ± 0.00 | 0.25 ± 0.00 |
Stride (s) | 0.36 ± 0.01 | 0.37 ± 0.01 | 0.34 ± 0.01 | 0.35 ± 0.01 |
Swing (s) | 0.11 ± 0.00 | 0.12 ± 0.01 | 0.10 ± 0.00 | 0.11 ± 0.00 |
Brake (s) | 0.06 ± 0.00 | 0.06 ± 0.00 | 0.06 ± 0.00 | 0.05 ± 0.00 |
Propel (s) | 0.19 ± 0.00 | 0.19 ± 0.00 | 0.18 ± 0.00 | 0.19 ± 0.00 |
Paw angle (°) | 10.28 ± 0.62 | 10.52 ± 0.83 | 11.73 ± 1.34 | 11.32 ± 0.76 |
Paw area (cm2) | 0.81 ± 0.03 | 0.92 ± 0.05 | 0.84 ± 0.05 | 0.86 ± 0.05 |
p < .05;
p < .01 vs. respective saline control.
p < .05;
p < .01 vs. respective wild-type control.