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T cells from the majority of healthy donors recognize peptides derived from mutant EZH2.
| Number of EZH2-reactive T cell lines generated |
||||
|---|---|---|---|---|
| Donor | Total | Y641F-reactive | Y641N-reactive | WT-reactive |
| DC011 | 7 | 7 | — | 0 |
| DC038 | 1 | 1 | — | 0 |
| DC044 | 9 | 9 | — | 0 |
| DC059 | 1 | 1 | — | 0 |
| DC041 | 6 | 6 | — | 3 |
| DC056 | 4 | 4 | — | 2 |
| DC023 | 30 | 30 | — | 30 |
| DC029 | 0 | 0 | — | 0 |
| DC054 | 0 | 0 | — | 0 |
| DC060 | 0 | 0 | — | 0 |
| DC040 | 4 | — | 4 | 0 |
| DC058 | 1 | — | 1 | 0 |
| DC035 | 4 | — | 4 | 1 |
| DC091 | 0 | — | 0 | 0 |
| Total | 67 | 58 | 9 | 36 |
