Figure 2. Plasma phospholipid level, plasma cholesterol level, and HDL particle concentration (HDL-P_IMA) of wild-type mice and mice deficient in APOA1, APOE, APOA1/APOE, or APOA4.

Phospholipid (A) and total cholesterol (B) levels were quantified biochemically. (C) HDL-P_IMA was determined by calibrated ion mobility analysis using glucose oxidase as the standard. Significance was determined by ANOVA followed by Fisher’s post-hoc analysis for multiple comparisons. *P < 0.05 versus wild-type mice (WT).