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. Author manuscript; available in PMC: 2018 Mar 28.
Published in final edited form as: Cancer Lett. 2016 Dec 30;389:41–48. doi: 10.1016/j.canlet.2016.12.030

Fig. 3.

Fig. 3

SRI36160 blocks Wnt/β-catenin signaling in colorectal cancer cells. DLD-1 and HCT116 cells were transiently transfected with the Super8XTOPFlash luciferase construct and the β-galactosidase-expressing vector in each well. After 24 h incubation, cells were treated with SRI36160 (A, B) at 0.11 – 2187 nM or LGK974 at 3 – 40,000 nM (C, D) for 24 h. The luciferase activity was then measured with normalization to the activity of the β-galactosidase. Values are the average of triple determinations with the SD indicated by error bars.