Table 2.
Comparison of laboratory data between fatal and surviving dengue hemorrhage fever cases in Kaohsiung, 2014–2015
| Characteristics | Fatal (N = 50) | Survival (N = 156) | P values |
|---|---|---|---|
| Initial AST (IU/L) | 764.1 ± 1,756.6 (50) | 306.9 ± 1,970.4 (150) | 0.007 |
| Maximum AST (IU/L) | 6,151 ± 8,207.8 (50) | 596.9 ± 2,799.2 (150) | < 0.0001 |
| Initial ALT (IU/L) | 233.2 ± 462.3 (49) | 104.8 ± 369.2 (154) | 0.014 |
| Maximum ALT (IU/L) | 1,549.8 ± 1,665.1 (49) | 188.8 ± 511.8 (153) | < 0.0001 |
| Serum blood urea nitrogen (mg/dL) | 39.7 ± 26.1 (49) | 21.1 ± 16.2 (139) | < 0.0001 |
| Serum creatinine (mg/dL) | 2.5 ± 1.9 (50) | 1.5 ± 1.6 (156) | < 0.0001 |
| Initial C-reactive protein (mg/dL) | 52.4 ± 67.1 (46) | 22.2 ± 27.9 (149) | 0.001 |
| Albumin (g/dL) | 3 ± 0.7 (37) | 3.3 ± 0.6 (102) | 0.01 |
| Initial white blood cells (/mm3) | 8,220.7 ± 4,731.9 (50) | 5,446.2 ± 2,914.9 (156) | < 0.0001 |
| Initial neutrophils (%) | 76.3 ± 18.5 (41) | 72.4 ± 14.6 (138) | 0.037 |
| Initial lymphocytes (%) | 12.2 ± 10.6 (44) | 16.1 ± 12 (143) | 0.023 |
| Initial monocytes (%) | 7.4 ± 7.9 (44) | 9.5 ± 8.5 (142) | 0.003 |
| Initial hemoglobin (g/L) | 12.7 ± 2.7 (50) | 13.3 ± 2.2 (156) | 0.04 |
| Initial hematocrit (%) | 37.6 ± 8.1 (50) | 39.3 ± 6.1 (156) | 0.05 |
| Initial platelets (/mm3) | 92.9 ± 73.1 (50) | 102.7 ± 71.3 (156) | 0.303 |
| Prolongation of PT* n/N (%) | 17/45 (37.8) | 12/99 (12.1) | < 0.0001 |
| Prolongation of APTT† n/N‡ (%) | 41/45 (91) | 86/98 (87.8) | 0.554 |
ALT = alanine aminotransferase; APTT = activated prothrombin time; AST = aspartate aminotransferase; PT = prothrombin time.
*
Prolongation of PT is defined as a PT > 3 seconds than that of control.
†
Prolongation of APTT is defined as APTT > 20% than that of control.
‡
No. of patients/no. of patients with data available.