Table 3.

Comparison of clinical characteristics between dengue hemorrhage fever cases in 2014 and in 2015

Characteristics	2014 (N = 113)	2015 (N = 93)	P values
Demographic and underlying diseases
Male (%)	58/113 (51.3%)	46/93 (49.5%)	0.79
Age (year)	63.8 ± 16.4 (113)	66.8 ± 14.1 (93)	0.234
Age ≥ 65 years	67/113 (59.3%)	61/93 (65.6%)	0.354
Diabetes mellitus	29/113 (25.7%)	40/93 (43.0%)	0.009
Hypertension	58/113 51.3%)	60/93 (64.5%)	0.057
Congestive heart failure	4/113 (3.5%)	9/93 (9.7%)	0.071
COPD	3/113 (2.7%)	6/93 (6.5%)	0.305*
CVA (Cerebral vascular accident)	7/113 (6.2%)	18/93 (19.4%)	0.004
ESRD (End stage renal disease)	4/113 (3.5%)	3/93 (3.2%)	1*
CKD stage 3, 4, or 5	53/113 (46.9%)	58/93 (62.4%)	0.027
Charlson comorbidity index score	4.37 ± 2.56	5.65 ± 2.44	< 0.0001
Clinical manifestations and management
ARF	8/113 (7.1%)	9/93 (9.7%)	0.5
Received hemodialysis after admission	5/113 (4.4%)	6/93 (6.5%)	0.52
Bacterial coinfection	12/113 (11%)	11/93 (11.8%)	0.784
Nosocomial infection	4/113 (3.5%)	7/93 (7.5%)	0.229*
Bacteremia	3/113 (2.65%)	2/93 (2.2%)	1*
EGD perform	13/113 (11.5%)	5/93 (5.4%)	0.121
PPI use	44/113 (38.9%)	64/93 (68.8%)	< 0.0001
NSAID use in emergency room	32/113 (28.3%)	31/93 (33.3%)	0.437
Platelet transfusion	47/113 (41.6%)	58/93 (62.4%)	0.003
PRBC transfusion	23/113 (20.4%)	28/93 (30.1%)	0.107
Mortality rate	14/113 (12.4%)	36/93 (38.7%)	< 0.0001
Admission duration (days)	10.2 ± 11.3 (113)	10.4 ± 10.7 (93)	0.386

ARF = acute renal failure; CKD = chronic kidney disease; COPD = chronic obstructive pulmonary disease; CVA = cerebral vascular accident; EGD = esophageal gastroduodenoscopy; ESRD = end-stage renal disease; NSAID = nonsteroidal anti-inflammatory drugs; PPI = proton pump inhibitor; PRBC = packed red blood cell.

^*Fisher’s exact test.